Therapeutic manipulation of angiogenesis with miR-27b
نویسندگان
چکیده
منابع مشابه
Therapeutic manipulation of angiogenesis with miR-27b
BACKGROUND Multiple studies demonstrated pro-angiogenic effects of microRNA (miR)-27b. Its targets include Notch ligand Dll4, Sprouty (Spry)-2, PPARγ and Semaphorin (SEMA) 6A. miR-27 effects in the heart are context-dependent: although it is necessary for ventricular maturation, targeted overexpression in cardiomyocytes causes hypertrophy and dysfunction during development. Despite significant ...
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ژورنال
عنوان ژورنال: Vascular Cell
سال: 2015
ISSN: 2045-824X
DOI: 10.1186/s13221-015-0031-1